Introduction - What is Mesothelioma?
Mesothelioma, a cancer that attacks the lining of the lung cavity, thorax, abdomen and is one of the best known of cancer in the world today. This is a fatal, incurable disease - some report statistics 9 of 10 patients with mesothelioma will die from the disease within one year of 3 Only 5% after 5 years of diagnosis.
Mesothelioma is flexible to asbestos, a,heat-resistant mineral fiber that has been widely used in various industries, including shipbuilding, and the mines to be found. Since the relationship between asbestos and mesothelioma was found to have numerous cases brought by victims of exposure to business executives. The new laws governing the use of asbestos has been adopted.
Since then, research on potential treatments for mesothelioma is continued, with varying results. One ofnew therapies will be investigated as an anti-angiogenic therapy known.
Angiogenesis
The term "anti-angiogenesis angiogenesis comes from a word that means the growth and development of new blood vessels. With the progress of tumors grow quickly moved off the blood supply to them through the blood vessels of the body, and need to grow their own system of blood vessels to obtain an adequate supply of oxygen and nutrients. Without these new blood vessels, the cancer can not growand distribute.
As anti-angiogenesis therapy Works
The anti-angiogenic therapy directed at preventing the growth of cancer cells of new blood vessels, causing slow or even stop the development of cancer. It does so by focusing on two chemicals in the body to regulate the growth of blood vessels: the basic fibroblast growth factor (FGF-2) and vascular endothelial growth factor (VEGF) tests. The chemical latter is particularly important for mesothelioma patients, havefound that people with mesothelioma VEGF show a much greater extent than patients with other types of cancer. These results indicate that VEGF mesothelioma may have a strong bond, and thus may be better to treatments that target VEGF.
An experimental drug tested against mesothelioma is to bevacizumab. This drug has been tested for use in patients with kidney, breast, ovarian, and prostate cancer, among others.Currently, the results of a study that was completed in 2005 and compared the efficacy of bevacizumab against two chemotherapy drugs (gemcitabine and cisplatin) have been analyzed and to be published.
Both the anti-angiogenic therapy is a viable treatment or cure for mesothelioma remains to be seen. While scientists struggle to fight mesothelioma, new ways for people to continue to suffer this much havoc.
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